Anatomopathological study was developed in 28 goats from 3 flocks naturally infected with Map. The goats that were positive to AGID, ELISA or both tests such as the ones that showed progressive weight loss were considered paratuberculosis infected and were necropsied. Jejune, ileum, ileocaecal valve, liver and mesenteric lymph nodes fragments were collected and stained with H-E and Z-N stains. Discrete to severe folding of the mucosa was observed, the subserosal lymphatic vessels were prominent. The mesenteric lymph nodes were enlarged, oedematous and the corticomedullar distinction was poor in most goats. Microscopically, the lesions consisted in focal granulomatous lesions on Peyer's patches and associated mucosa with scarce AFB, zonal granulomatous enteritis with moderate to abundant AFB, and diffuse severe granulomatous enteritis with moderate and abundant AFB. In the mesenteric lymph nodes the lymphoid cells within the paracortical zone were discrete to largely replaced by macrophages and giant cells, scarce to abundant afb were observed; eventually, discrete foci of necrosis and mineralisation were present such as foreign body giant cells. Liver lesions consisted in periportal mononuclear infiltrate and one goat showed multifocal granulomatous hepatitis with foreign body giant cells and abundant AFB. The lesions above described agree with the ones reported in goats naturally infected with Map. Necrosis, caseation and ulceration as they occur in tuberculosis were always absent.